Failure of Repeated Treatment With Praziquantel and Arthemeter in Four Patients With Acute Schistosomiasis

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Disappearance of specific antibodies in patients with chronic schistosomiasis japonica by treatment with praziquantel.

We tested effects of praziquantel, an antischistosomal compound, on clinical and immunological parameters of chronic schistosomiasis japonica. Two Japanese patients, who had high antibody titers to Schistosoma japonicum antigens but no fecal schistosome eggs or no or mild symptoms complained, were treated with praziquantel. Within two years after treatment, anti-schistosome antibodies in sera f...

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A double-blind clinical trial involving 120 patients with chronic schistosomiasis was carried out to compare the tolerability and efficacy of praziquantel and oxamniquine. The patients were randomly allocated into two groups. One was treated with praziquantel, 55 mg/kg of body weight CBWT), and the other one with oxamniquine, 15mg/kg bwt, administered in a single oral dose. The diagnosis and th...

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ژورنال

عنوان ژورنال: Journal of Travel Medicine

سال: 2014

ISSN: 1195-1982,1708-8305

DOI: 10.1111/jtm.12098